Allele Frequency Estimation by Borrowing Strength Across Populations
Neyman Seminar
Mar 17, 2010, 04:00 PM - 05:00 PM | 1011 Evans Hall | Happening As Scheduled
Marc Coram, Health Research & Policy - Biostatistics, Stanford University (Speaker)
In genetic studies, allele frequency at a genetic marker is
routinely inferred, often using genotypes from a small set of
individuals. Improving the accuracy of these estimates will benefit
studies of human genetic variation or the genetic etiology of
heritable traits. Here, we propose an empirical Bayes approach for
estimating allele frequencies at single nucleotide polymorphisms....