BMCP: A Segmentation Algorithm for SNP Microarray Copy Number Data from Cancer Studies

BMCP: A Segmentation Algorithm for SNP Microarray Copy Number Data from Cancer Studies

Statistics and Genomics Seminar
Sep 22, 2011, 04:10 PM - 05:00 PM | 1011 Evans Hall | Happening As Scheduled
Yu Chuan Tai, Roche Molecular Diagnostics
High-density SNP microarrays provide a useful tool for the detection of copy number changes in tumors. We propose an algorithm called BMCP, for segmentation and estimation of SNP microarray copy number data from cancer studies. Segmentation concerns separating a chromosome into regions of equal copy number differences between the sample of interest and some reference, and involves the detection...