Characterization of Allele-Specific Copy Number in Tumor Genomes

Characterization of Allele-Specific Copy Number in Tumor Genomes

Neyman Seminar
Jan 27, 2010, 04:00 PM - 05:00 PM | 1011 Evans Hall | Happening As Scheduled
Nancy Zhang, Department of Statistics, Stanford University (Speaker)
Chromosomal gains and losses comprise an important type of genetic change in tumors, and can now be assayed using microarray hybridization based experiments. Most current statistical models for DNA copy number estimate total copy number, which do not distinguish between the underlying quantities of the two inherited chromosomes. This latter information, which we call...