Gene Expression Profiles from Formalin Fixed Paraffin Embedded Breast Cancer Tissue Are Largely Comparable to Fresh Frozen Matched Tissue
Statistics and Genomics Seminar
Mar 31, 2011, 04:00 PM - 05:00 PM | 1011 Evans Hall | Happening As Scheduled
Dr. Lorenza Mittempergher, Departments of Pathology and Laboratory Medicine, UCSF (Speaker)
Formalin Fixed Paraffin Embedded (FFPE) samples represent a valuable resource for cancer research. However, the discovery and development of new cancer biomarkers often requires fresh frozen (FF) samples. Recently, the Whole Genome (WG) DASL (cDNA-mediated Annealing, Selection, extension and Ligation) assay was specifically developed to profile FFPE tissue. However, a thorough comparison of data...