MOSAiCS: Model-based One and Two Sample Analysis and Inference for ChIP-Seq data: background adjustment, peak calling, and multi-reads
Neyman Seminar
Oct 27, 2010, 04:10 PM - 05:00 PM | 1011 Evans Hall | Happening As Scheduled
Sundez Keles, Department of Statistics and Department of Biostatistics, Univeristy of Wisconsin-Madison (Speaker)
Chromatin immunoprecipitation followed by sequencing (ChIP-Seq) has revolutionized experiments for genome-wide profiling of DNA-binding proteins, histone modifications, and nucleosome occupancy. As the cost of sequencing is decreasing, many researchers are switching from microarray-based technologies (ChIP-chip) to ChIP-Seq for genome-wide study of transcriptional regulation. Despite its...