Non-Parametric Modelling of Gene Expression during Cellular Development from Single-Cell RNA-Seq

Non-Parametric Modelling of Gene Expression during Cellular Development from Single-Cell RNA-Seq

Statistics and Genomics Seminar
Oct 13, 2016, 04:00 PM - 05:00 PM | 1011 Evans Hall | Happening As Scheduled
Valentine Svensson, European Molecular Biology Laboratory (EMBL) - European Bioinformatics Institute (EBI), Hinxton, UK
Cells are defined to be in certain states depending on their phenotypes. As cells develop from one state to another, the molecular composition is changed due to transcriptional regulation, modulating the output of mRNA. During these transition, which can be due to natural temporal processes or a response to a stimulus, the abundance of different mRNA species will change in dynamic ways....