Quantifying patterns of tumour evolution

Quantifying patterns of tumour evolution

Statistics and Genomics Seminar
Feb 18, 2016, 04:00 PM - 05:00 PM | 1011 Evans Hall | Happening As Scheduled
Florian Markowetz, Cancer Research UK, Cambridge Institute (Speaker)
Cancer has long been understood as a somatic evolutionary process, but many details of tumor progression remain elusive. Here, I will talk about computational methods to infer evolutionary pathways leading to tumour heterogeneity. I will start by discussing how to quantify intra-patient heterogeneity by rigorous analysis of copy-number profiles from multiple patient samples. Using a study in...