Learning about the Genetic Architecture of Complex Traits Across Populations

Learning about the Genetic Architecture of Complex Traits Across Populations

Statistics and Genomics Seminar
May 5, 2016, 04:00 PM - 05:00 PM | 1011 Evans Hall | Happening As Scheduled
Hua Tang, Department of Genetics, Stanford University
Genome-wide association studies (GWAS) have become a standard approach for identifying loci influencing complex traits. However, GWAS in non-European populations are hampered by limited sample sizes and are thus underpowered. Can GWAS results in one population be exploited to boost the power of mapping loci in another population? We introduce an empirical Bayes approach, which improves the power...